Transseptal Catheterization and Interventions

Edited by Ranjan Thakur, MD; Andrea Natale, MD
Foreword by Eugene Braunwald, MD

Published September 2010

Format: Hardcover; eBook

Trim Size: 7 X  10 inches

ISBN: 9780979016417

256 pages, 350 illustrations/figures/tables, full color interior

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The first comprehensive resource on transseptal catheterization.

Although the transseptal technique was described half a century ago, it has remained essentially unchanged. Recent advances in cardiac electrophysiology and left heart interventions have led to renewed interest in the technique as a means of delivering modern therapeutic interventions.

Until now, the knowledge required for safely gaining access to the left atrium to perform catheter ablation for atrial fibrillation or other interventions has existed only in original publications and review articles. This textbook brings all of the relevant information about this technique under one cover, with top experts in each area addressing anatomy, indications, transseptal puncture, visualization technologies, interventional devices, challenging cases, complications, and emerging tools. Electrophysiologists and interventional cardiologists will find Transseptal Catheterization and Interventions invaluable for their work. For teachers and trainees, it will be a welcome teaching tool and resource.

Transseptal Catheterization and Interventions was listed by the American Journal of Cardiology as one of the "Good Books in Cardiovascular Disease in 2010". - American Journal of Cardiology Vol. 107, Issue 8, Pages 1250-1251

Transseptal left heart catheterization is here to stay. It already plays an important role in the repertoire of both interventional cardiologists and clinical electrophysiologists, and it will play an increasingly important role in the future.

Transseptal Catheterization and Interventions is the first book on this subject. The editors, Drs. Thakur and Natale, as well as their talented authors, should be congratulated for providing such an excellent and eminently readable volume. . . . I can’t wait for the next edition.

-- From the foreword by Eugene Braunwald MD
Distinguished Hersey Professor of Medicine, Harvard Medical School, Boston, Massachusetts

A lost art among many interventional cardiologists trained in the current era, transseptal catheterization has reemerged as a critical step in several structural heart procedures. This book beautifully summarizes the key concepts behind successfully performing transseptal catheterization and interventions and revives what will be an increasingly important tool in the interventionalist’s armamentarium. All interventional cardiologists should have this book in their catheterization laboratories.

-- Deepak L. Bhatt MD, MPH
Associate Professor of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts


Ranjan Thakur, MD, MPH, MBA, FHRS; Professor of Medicine and Director, Electrophysiology Fellowship, Thoracic and Cardiovascular Institute, Sparrow Health System, Michigan State University, Lansing, Michigan

Andrea Natale, MD, FACC, FHRS; Executive Medical Director, Texas Cardiac Arrhythmia Institute, St. David’s Medical Center, Austin, Texas; Consulting Professor, Division of Cardiology, Stanford University, Stanford, California; Clinical Associate Professor of Medicine, Case Western Reserve University, Cleveland, Ohio; Senior Clinical Director, EP Services, California Pacific Medical Center, San Francisco, California; and Director of Interventional EP, Scripps Green, San Diego, California

Table of Contents:

1. History of Transseptal Catheterization
Gregory K. Feld MD, John Ross Jr MD

2. Embryology and Anatomy of the Atrial Septum
Siew Yen Ho PhD

3. Radiographic Anatomy of the Atria for the Interventional Electrophysiologist
Isabelle Nault MD, Pierre Jaïs MD, Sébastien Knecht MD

4. Indications and Contraindications for Transseptal Catheterization
Hakan Oral MD, Michael Kühne MD

5. Equipment for Transseptal Punctures
David Callans MD, Peter Leong-Sit MD

6. Fluoroscopy-Guided Transseptal Catheterization
Kalyanam Shivkumar MD, Michael M. Shehata MD

7. Transseptal Catheterization Guided by Transthoracic and Transesophageal Echocardiography
Bradley P. Knight MD, Matthew P. Smelley MD

8. Intracardiac Echocardiography to Guide Transseptal Puncture
Andrea Natale MD, Conor D. Barrett MD, Luigi Di Biase MD, J. David Burkhardt MD, Rodney P. Horton MD, Sheldon M. Singh MD, Moussa Mansour MD

9. Transseptal Catheterization in Electrophysiology Procedures in Children and Patients with Congenital Heart Disease
Edward P. Walsh MD, Richard J. Czosek MD, John K. Triedman MD

10. Challenging Transseptal Catheterizations
Yu-Feng Hu MD, Ming-Hsiung Hsieh MD, Shih-Ann Chen MD

11. Transcatheter Atrial Septal Defect Device Closure
Ziyad M. Hijazi MD, Sawsan M. Awad MD, Qi-Ling Cao MD

12. Transseptal Left Heart Interventions
Mehul B. Patel MD, Tahmeed Contractor MD, Samin K. Sharma MD

13. Percutaneous Left Atrial Appendage Occlusion Devices
Rodney Horton MD, Javier E. Sánchez MD, Yan Wang MD, Andrea Natale MD

14. Novel Approaches and Technology for Transseptal Catheterization
Vivek Y. Reddy MD, Sheldon M. Singh MD

15. Complications of Transseptal Catheterization
Ranjan Thakur MD, Mehul B. Patel MD, Khyati Pandya MD, Atul Khasnis MD


5-Star Doody Rating (100/100)

This textbook is a valuable resource that is long overdue. The clear writing provides a detailed, pragmatic guide to transseptal procedures. Numerous superb illustrations simplify the anatomy and the technical approaches. The emphasis on tips and tricks, along with complications and unusual situations, creates a practical text for both the novice and advanced interventionalist.

-- Paul Teirstein MD
Chief of Cardiology, Scripps Clinic, La Jolla, California

Dealing with all aspects of transseptal catheterization, this book is a complete manual in a rapidly expanding area. It is authored by prominent leaders in the field and fills a gap in the medical literature. It is a practical guide for interventional cardiologists and electrophysiologists and a reference text for general cardiologists, fellowship trainees, medical students, nurses, and others.

-- Antonio Raviele MD
Chief, Cardiovascular Department, Arrhythmia Center & Center for Atrial Fibrillation, Ospedale dell’Angelo, Mestre, Italy

Transseptal catheterization is an indispensable procedure in the modern catheterization and electrophysiology laboratory. Although considered routine by many, the procedure demands skill and familiarity with the regional anatomy and its variants. In the best of hands, it is sobering to remember that one is only a heartbeat away from a disastrous complication.

In this unique and timely book, a top-tier group of authors covers the landscape of the necessary cognitive and technical tools to perform this procedure safely and skillfully. The book represents a concise and readable one-stop resource for any individual who wishes to perform or teach this procedure.

-- George J. Klein MD
Professor of Medicine, University Hospital, London, Ontario, Canada

Timir Paul,  MD, PhD, MPH(East Tennessee State University Quillen College of Medicine)

This multiauthored reference on transseptal catheterization and interventions includes contributions from national and international thought leaders in cardiac electrophysiology and interventions.

This book includes an up-to-date review of embryology and anatomy of the interatrial septum, various methods, illustrations of difficult cases, complications, and new technologies for safety and efficacy of transseptal catheterization and interventions.

The intended audience includes both adult and pediatric interventional cardiologists and electrophysiologists in training or in practice who perform transseptal catheterization.

The first few chapters focus on embryology and anatomy of the interatrial septum, radiographic anatomy of the atria, indications, contraindications, and equipment for transseptal catheterization. Subsequent chapters provide detailed discussions about various methods, illustrations of challenging cases, complications, and new technologies. The last few chapters cover transseptal techniques in pediatric cardiology, emerging applications in interventional cardiology, and left atrial appendage closure. Numerous figures and illustrations of fluoroscopic images and echocardiograms are easy to understand and concepts are nicely detailed. Flow charts for the important steps and precautions for transseptal interventions as well as schematic representation of these procedures are very easy to follow. The comparative images of fluoroscopy, cardiac CT, and different modalities of echocardiograms help clarify the concepts of atrial anatomy pertinent to transseptal catheterization and the steps in interventions. Tabulated forms of trouble-shooting problems, causes, and solutions are very helpful without going through the text.

This will be a valuable resource for physicians interested in performing transseptal catheterization procedures. The authors meet their objective of providing a high quality, comprehensive book on the subject.